bedtools

Version:

2.30.0, 2.37

Category:

bio

Cluster:

Loki

Author / Distributor

https://bedtools.readthedocs.io/_/downloads/en/stable/pdf/

Description

A flexible suite of utilities for comparing genomic features. Collectively, the bedtools utilities are a swiss army k nife of tools for a wide-range of genomics analysis tasks.

Documentation

Usage:     bedtools <subcommand> [options]

The bedtools sub-commands include:

[ Genome arithmetic ]
   intersect     Find overlapping intervals in various ways.
   window        Find overlapping intervals within a window around an interval.
   closest       Find the closest, potentially non-overlapping interval.
   coverage      Compute the coverage over defined intervals.
   map           Apply a function to a column for each overlapping interval.
   genomecov     Compute the coverage over an entire genome.
   merge         Combine overlapping/nearby intervals into a single interval.
   cluster       Cluster (but don't merge) overlapping/nearby intervals.
   complement    Extract intervals _not_ represented by an interval file.
   shift         Adjust the position of intervals.
   subtract      Remove intervals based on overlaps b/w two files.
   slop          Adjust the size of intervals.
   flank         Create new intervals from the flanks of existing intervals.
   sort          Order the intervals in a file.
   random        Generate random intervals in a genome.
   shuffle       Randomly redistribute intervals in a genome.
   sample        Sample random records from file using reservoir sampling.
   spacing       Report the gap lengths between intervals in a file.
   annotate      Annotate coverage of features from multiple files.

[ Multi-way file comparisons ]
   multiinter    Identifies common intervals among multiple interval files.
   unionbedg     Combines coverage intervals from multiple BEDGRAPH files.

[ Paired-end manipulation ]
   pairtobed     Find pairs that overlap intervals in various ways.
   pairtopair    Find pairs that overlap other pairs in various ways.

[ Format conversion ]
   bamtobed      Convert BAM alignments to BED (& other) formats.
   bedtobam      Convert intervals to BAM records.
   bamtofastq    Convert BAM records to FASTQ records.
   bedpetobam    Convert BEDPE intervals to BAM records.
   bed12tobed6   Breaks BED12 intervals into discrete BED6 intervals.

[ Fasta manipulation ]
   getfasta      Use intervals to extract sequences from a FASTA file.
   maskfasta     Use intervals to mask sequences from a FASTA file.
   nuc           Profile the nucleotide content of intervals in a FASTA file.

[ BAM focused tools ]
   multicov      Counts coverage from multiple BAMs at specific intervals.
   tag           Tag BAM alignments based on overlaps with interval files.

[ Statistical relationships ]
   jaccard       Calculate the Jaccard statistic b/w two sets of intervals.
   reldist       Calculate the distribution of relative distances b/w two files.
   fisher        Calculate Fisher statistic b/w two feature files.

[ Miscellaneous tools ]
   overlap       Computes the amount of overlap from two intervals.
   igv           Create an IGV snapshot batch script.
   links         Create a HTML page of links to UCSC locations.
   makewindows   Make interval "windows" across a genome.
   groupby       Group by common cols. & summarize oth. cols. (~ SQL "groupBy")
   expand        Replicate lines based on lists of values in columns.
   split         Split a file into multiple files with equal records or base pairs.
   summary       Statistical summary of intervals in a file.

[ General Parameters ]
    --cram-ref    Reference used by a CRAM input

[ General help ]
   --help        Print this help menu.
   --version     What version of bedtools are you using?.
   --contact     Feature requests, bugs, mailing lists, etc.

Examples/Usage

  • List available modules:

    $ module avail bedtools
    
  • Load the Bedtools module:

    $ module load bio/bedtools/2.30.0
    
  • Check the loaded modules:

    $ module list
    
  • Unload the bedtools module:

    $ module unload bio/bedtools/2.30.0
    

Installation

Source code is obtained from Bedtools